| Active Ingredient | Ivabradine |
| Brand | Ivabriz |
| Country of origin | India |
| Form | Oral tablets |
Ivabriz contains ivabradine, a medicine that helps reduce heart rate. It is commonly prescribed for heart conditions. This oral tablet should only be used after consulting a doctor.
Clinical Uses
Ivabradine is used for treating chronic heart failure. It is also used in the treatment of chronic stable angina pectoris in patients to reduce heart rate and improve exercise tolerance.
Dosage Strengths
Ivabriz tablet is available in the dosage strength of 5mg and 7.5mg. Consult a doctor to know which is the right dosage strength for you.
How It Works
Ivabradine inhibits the If channels in the sinoatrial (SA) node of the heart, slowing the spontaneous electrical activity that controls the heartbeat. This reduces the heart rate and decreases the heart’s oxygen demand without significantly affecting the force of cardiac contraction.
Side Effects
Common side effects include bradycardia (slow heart rate), dizziness, fatigue, and visual disturbances such as temporary brightness or flashes of light (phosphenes). It may also cause atrial fibrillation and low blood pressure.
Precautions & Warnings
- Monitor your heart rate regularly, as this medicine may cause excessive slowing of the heart rate (bradycardia).
- Use after consulting a doctor if you suffer from low blood pressure or a history of irregular heart rhythms.
- Avoid use during pregnancy and breastfeeding unless advised by a healthcare professional.
- Inform the doctor about any existing liver or kidney problems.
- Avoid grapefruit and grapefruit juice, as they may increase the medicine’s concentration in the blood.
- This medicine may cause dizziness and drowsiness. So drive with caution.
Drug Interactions
Taking other medicine and supplements with Ivabriz tablet can cause an drug interaction. Some of the medicine that doctors do not advise taking with Ivabriz tablet include-
- Medicines such as clarithromycin, ketoconazole, and itraconazole may increase ivabradine levels and the risk of bradycardia.
- Rifampicin, phenytoin, and carbamazepine may reduce ivabradine levels and its effectiveness.
- Beta-blockers, verapamil, and diltiazem may increase the risk of excessive slowing of the heart rate. Verapamil and diltiazem should not be used with ivabradine.
- Some medicines that prolong the QT interval may increase the risk of abnormal heart rhythms, especially when the heart rate is slow.
Note that this is not all the medicines that can interact with Ivabriz tablet. Before you take any medicine with Ivabriz, consult a doctor.
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