| Active Ingredient | Pyrazinamide |
| Brand | Prinide |
| Country of origin | India |
| Form | Oral Tablet |
Prinide tablets contains Pyrazinamide, a first line of anti tubercular agent that treats active tuberculosis infection.
Clinical Uses
Pyrinide tablets is used for treating active tuberculosis in combination with other medicines such as Isoniazid and Rifampicin. It is used during the initial intensive phase of TB treatment. The role of Pyrinide is important in shortening the duration of treatment.
Dosage Options
The dosage options for Pyrinide tablets include 500mg, 750mg, and 1000mg. The right dosage option for you should be decided by your doctor depending on the severity of the condition. Do not take this medicine without consulting a healthcare professional.
How It Works
Pyrinide is a prodrug that is converted by the enzyme pyrazinamidase into its active form pyrazinoic acid. It works in an acidic environment and affects the energy production and survival of Mycobacterium tuberculosis which causes TB. This helps to kill TB bacteria and manage infection.
Side Effects
The common side effects may include-
- Nausea
- Loss of appetite
- Vomiting
- Mild joint pain
In rare cases it may cause gout, liver toxicity, and allergic skin reaction. If any of these side effects lasts for too long then consult a doctor.
Precautions & Warnings
- Avoid having alcohol while on this treatment as it can increase the risk of liver damage.
- During this treatment it is important to regularly monitor the liver function and uric acid levels.
- Pregnant and lactating mothers should always consult a doctor before taking this TB medicine.
- Patients with kidney, liver, and heart issues should use this medicine with caution.
- This medicine can cause dizziness and drowsiness. So, avoid driving or using any heavy machines while using this medicine.
Drug Interactions
Some of the medicines that you should not take while taking Pyrinide tablets include-
- ketoconazole
- leflunomide
- mipomersen
- lomitapide
- rifampin
- pexidartinib
- teriflunomide
- mycophenolic acid
This is not a complete list of all the possible drug interactions of Pyrinide tablet. Before taking any medicine or supplement with this medicine consult a doctor.
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