| Bucelon 2 mg | |
| Active ingredient | Bussulphan |
| Brand | Bucelon |
| Country of origin | India |
| Form | Oral tablet |
Bucelon 2 mg is an anti-cancer chemotherapy drug. It is an alkyl sulfonate that belongs to the drug class called alkylating agent. It is a prescribed treatment to prepare the bone marrow to receive healthy blood-forming cells from a donor. It is usually used to replace their stem cells that have been destroyed by treatment wth radiation
Clinical Uses
The following are the uses of Bucelon tablet help to manage the conditions such as:
- Chronic myeloid leukaemia (CML):
It helps to manage this chronic cancer of the white blood cells by slowing down the overproduction of abnormal cells in the bone marrow.
- In certain cases, doctors might use this medicine to help prepare the body for a bone marrow or stem cell transplant by clearing out diseased cells.
How It Works?
Bucelon works by interfering with the DNA replication process, which is necessary for the cells to divide. It stops the tumour growth by inhibiting cell division. It causes cytotoxicity by reversibly binding to nucleophilic groups on different cell components. Alkylation of DNA is most likely the crucial cytotoxic reaction that kills tumor cells. It damages the RNA and DNA of the cancer cells by stopping their growth and multiplication.
Side Effects
Below are some of the side effects of Bucelon 2 mg:
- Low platelet count
- Low white blood cells
- Bone marrow suppression
- Loose/watery stools
- Yellowing of the skin and eyes
- Jaundice
- Idiopathic pneumonia syndrome
Precautions & Warnings
The following are the precautionary measures that you need to keep in mind before taking Bucelon tablets:
- You will require regular frequent blood tests to monitor your blood cell counts and kidney or liver function.
- Avoid contact with sharp objects, this medicine reduces blood platelets, you will bruise and bleed more easily.
- Talk to your doctor before getting any vaccinations. This medicine might weaken your immune system and can cause serious infections.
- Both men and women taking this tablet must use highly effective birth control during treatment and for a specified time afterward.
Drug Interactions
The following are the medicines that might interact with Bucelon 2 mg:
- Acetaminophen.
- Antifungal medicines such as itraconazole or ketoconazole
- Seizure medicines like phenytoin.
Always consult a doctor before taking any medications along with Bucelon 2 mg.
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